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Human erythrocyte hemoglobin in the deoxy (1a3n) and oxy (1thb) states

• What structural elements are present in each molecule?
• What is the subunit composition?
• What is the coordination geometry about each metal ion?
• What is the distance between metal centers?
• What changes occur upon oxygenation?
• What are the characteristics of the allosteric effector (2,3-bisphosphoglycerate or inositol hexaphosphate) binding region?

Waller, D. A., and R. C. Liddington. 1990. Refinement of a partially oxygenated T state human haemoglobin at 1.5 Å resolution. Acta Crystallogr. B 46:409-418.

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