Yeast copper chaperone for Sod and CuZnSod structure

ChimeSquare.com^TM

Chime Square^TM Animations

Molecular Graphics Resource

Eric C. Niederhoffer, Ph.D.

Ecnhoffer@chimesquare.com
Copyright 2000- , E.C. Niederhoffer.
All Rights Reserved. All trademarks and copyrights are the property of their respective owners.

Complex between yeast copper chaperone for superoxide dismutase, yCCS, and a H48F mutant of copper,zinc superoxide dismutase (1jk9) from Saccharomyces cerevisiae

What structural elements are present in the protein?
What is the subunit composition?
What are the ligands for metal binding?
Which subunits correspond to yCCS and to SOD1?
What is the distance between motif (CXC and MHCXXC) cysteines and the metal binding sites?

Lamb, A. L., A. S. Torres, T. V. O'Halloran, and A. C. Rosenzweig. 2001. Heterodimeric structure of superoxide dismutase in complex with its metallochaperone Nat. Struct. Biol. 8:751-755.

yCCS-SOD1 (CuZnSod) (1jk9)

Alternate Views

Push the button to observe the following residues within 3 Å of Zn²⁺ centers (chain coloring, two chains omitted):

Asp83, Glu42, His16, His63, His71, His80

Push the button to observe the CXC motif of domain III (chain coloring):

Cys57, Cys229, Cys231

Push the button to observe the MHCXXC motif of domain I:

Cys17, Cys20, Cys27, Cys64

Push button

for Original View

chimesquare.com

For more information or comments about this page contact:
ChimeMaster@chimesquare.com

ChimeSquare.comTM

Chime SquareTM Animations

Molecular Graphics Resource

Eric C. Niederhoffer, Ph.D.

yCCS-SOD1 (CuZnSod) (1jk9)

ChimeSquare.com^TM

Chime Square^TM Animations