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Eric C. Niederhoffer, Ph.D.

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Cobalamin-containing methylmalonyl-coenzyme A mutase (1req) from Propionibacterium freudenreichii shermanii

Mancia, F., N. H. Keep, A. Nakagawa, P. F. Leadlay, S. McSweeney, B. Rasmussen, P. Bosecke, O. Diat, and P. R. Evans. 1996. How coenzyme B12 radicals are generated: the crystal structure of methylmalonyl-coenzyme A mutase at 2 Å resolution. Structure 4:339-350.

Methylmalonyl-coenzyme A mutase (1req)

Active Site View

  • Push the button  to observe the following residues within 3.0 Å of the cobalamin:
Ala139, Ala373, Arg207, Glu370, Gly609, His610, Leu657, Ser655, Thr709, Tyr89, Val206, and nine water molecules

Push button  for Original View

 

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