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Catabolite gene activator protein in the absence (1g6n) and presence of DNA (1ber) from Escherichia coli

• What structural elements are present in the protein?
• What is the subunit composition?
• What is the distance between protein and DNA?
• What characteristics can be discovered regarding the structure of DNA in the complex?
• Can you locate the coactivator?

Passner, J. M., S. C. Schultz, and T. A. Steitz. 2000. Modeling the cAMP induced allosteric transition using the crystal structure of CAP-cAMP at 2.1 Å resolution. J. Mol. Biol. 304:847-859.

Parkinson, G., C. Wilson, A. Gunasekera, Y. W. Ebright, R. E. Ebright, and H. M. Berman. 1996. Structure of the CAP-DNA complex at 2.5 Å resolution: a complete picture of the protein-DNA interface. J. Mol. Biol. 260:395-408.

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